• Poluchenie novykh tipov kondensirovannykh geterotsiklicheskikh soedineniy yavlyaetsya odnoy iz vazhneyshikh zadach organicheskoy khimii. Ispol'zovanie reaktsii vnutrimolekulyarnogo tsikloprisoedineniya v etom sluchae mozhet byt' osobenno polezno. Predstavlennaya rabota posvyashchena polucheniyu proizvodnykh 1,2,4,5-tetrazina, soderzhashchikh razlichnye dienofil'nye fragmenty. Eti soedineniya, v svoyu ochered', sposobny vstupat' v reaktsiyu vnutrimolekulyarnogo tsikloprisoedineniya s obratnymi elektronnymi trebovaniyami, gde 1,2,4,5-tetrazinovyy fragment vystupaet v roli geterodiena. V rezul'tate byli polucheny proizvodnye piridazinov, legkost' obrazovaniya kotorykh obuslovlena tem, chto vnutrimolekulyarnaya tsiklizatsiya protekaet bez stericheskikh zatrudneniy.
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  • V knige rassmatrivayutsya: Aktual'nye dannye po opredeleniyu i sravnitel'nomu analizu polnykh genomov predstaviteley Borrelia burgdorferi sensu lato; Epidemiologiya Laym borrelioza po dannym detektsii patogenov s ispol'zovaniem metodov molekulyarnoy biologii, vklyuchaya podrobnye dannye mnogoletnikh issledovaniy zarazhennosti rezervuarnykh khozyaev i perenoschikov na territorii Rossii, a takzhe dannye po SShA i Chili; Metodicheskie podkhody k issledovaniyu funktsiy genov Borrelia, v chastnosti ispol'zuemye dlya takikh rabot avtonomno replitsiruyushchiesya vektory, selektivnye markery i reporternye geny, integriruyushchiesya v genom Borrelia transpozony; Ispol'zovanie anti-smyslovykh RNK dlya upravleniyu ekspressiey genov Borrelia in vitro i in vivo na primere regulirovaniya ekspressii gena flaB i issledovaniya vliyaniya izmeneniy urovnya ego ekspressii na fenotip kletok Borrelia.
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    8777 РУБ.

  • This book, comprising two volumes, presents current research and original investigations in the theory of large cracks capable of propagating and initiating partial or complete fracture in deformable solids. The book covers a wide variety of problems relating to the behavior of bodies with cracks, and ranges from crack extension criteria to the solution of complex problems of fracture mechanics. Also, the authors consider critical and subcritical states of equilibrium under single, multiple, thermal and dynamic loadings in elastic, viscoelastic, elastic-plastic and piezoelectrical bodies with cracks. Experimental methods for the determination of crack-resistance characteristics of materials are exposed.The second volume, which we present to the reader, contains a systematic study of special problems of fracture mechanics, among which are the effects of hydrogen-containing environment, the corrosion in presence of electromagnetic fields, thermal and dynamical loadings, electromagnetic interaction in piezoelectrical bodies, and others. The solution of these problems is entailed with considerable mathematical difficulties. For this reason, a high level of mathematical knowledge is required. The first volume, published as a separate book, contains the main criteria and methods of elastic and elastic-plastic fracture mechanics.The book is intended for scientists and practicing engineers working in the field of fracture mechanics and also for post-graduates and senior students spec...
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    783 РУБ.

  • This book, comprising two volumes, presents current research and original investigations in the theory of large cracks capable of propagating and initiating partial or complete fracture in deformable solids. The book covers a wide variety of problems relating to the behavior of bodies with cracks, and ranges from crack extension criteria to the solution of complex problems of fracture mechanics. Also, the authors consider critical and subcritical states of equilibrium under single, multiple, thermal and dynamic loadings in elastic, viscoelastic, elastic-plastic and piezoelectrical bodies with cracks. Experimental methods for the determination of crack-resistance characteristics of materials are exposed. The first volume, which we present to the reader, is dedicated to the main criteria and methods of elastic and elastic-plastic fracture mechanics. Using real examples, the authors show the result of applying different fracture criteria for determining the critical and permissible length of a fracture under static or cyclic loadings. The second volume, published as a separate book, contains a systematic study of special problems of fracture mechanics. The book is intended for scientists and practicing engineers working in the field of fracture mechanics and also for post-graduates and senior students specializing in solid mechanics and strength of machine parts.
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    794 РУБ.

  • Since the Russian annexation of Crimea in 2014 and the beginning of the war in Donbas, Eastern Europe has been facing a migration crisis. Millions of Ukrainians are internally displaced or have fled the country and now face an uncertain future. At the same time, Western-imposed sanctions and the creation of the Eurasian Economic Union have affected Russia’s migration policies. These largely ignored processes have a potential to change the social landscape of the region for many years to come.The aim of this collection is to shed light on the forgotten migrant crisis at the European Union’s doorstep and make sense of the various migration processes in and out of Ukraine and Russia. The book is divided into two sections. The first section deals with migration processes that have taken place within Ukraine or have involved Ukrainian citizens’ migration out of the country, excluding Russia. The second section discusses Russia’s response to the rapid inflow of migrants from Ukraine, its changing migration policies and their effect on migrants, as well as other processes related to the phenomenon over the course of the Ukraine crisis.ContributorsTania Bulakh, Mikhail Denisenko, Joanna Fomina, Michael Gentile, Kateryna Ivashchenko-Stadnik, Marina A. Kingsbury, Irina Kuznetsova, Viacheslav Morozov, Vladimir Mukomel, Olga Oleinikova and Caress Schenk.
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  • The World Psychiatry Association has decided to publish a collection of anthologies of the fundamental texts of international psychiatric literature. These selected extracts will be published in each country simultaneously in the language in which they were written and in English translation, so that readers around the world for whom the working language of the World Association is more familiar, will find them easily accessible, yet may refer where appropriate to the original version. It may even be hoped that these extracts will prompt many psychiatrists to read the works from which they were taken in full. This will enable them to rediscover forgotten authors who introduced into psychopathology concepts which we continue to use, without always knowing their precise origin. In the case of authors who are well-known or at least still quoted today, the reader will also be able to discover what exactly they wrote, for such quotations are often inaccurate, and it is a surprise to find, in referring to the actual text from which they were taken, that the author’s thinking is quite different from that attributed to him, particularly in quotations of quotations.Издательство: Les Empecheurs Penser en Rond
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